The shifting sands of the Sonoran desert make the perfect setting for WCET’s 20th anniversary conference celebrating e-learning’s major contributions over the last two decades and its bright potential for further transforming higher education in the years ahead. In this era of accelerating change driven by new technologies and the creative genius of individuals who apply them, we must be bold in our search for best practices, in questioning common practices and in embracing new ways that e-learning and associated policies and services can erase academe’s limitations and increase its contribution to the world.